Best practice for securing your WebOffice 10 R3 web application if you decide to make it available in the Internet is to use a Reverse Proxy Web server. Thanks to Esri Inc. for the diagram for such a network infrastructure (see figure below).

Reverse proxy architecture
The Reverse Proxy architecture enables you to run Intranet AND Internet services using only one (1) server installation. This reduces TCO (Total Cost of Ownership) significantly (compared to the alternative to double the server and software infra structure).